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trial homepage | FAQ
the donor need to be a relative?
can consent patients to the REPAIR trial?
can carry out the intervention (Remote Ischaemic Preconditioning)?
do I do if I have problems accessing the on line REPAIR data collection
site, or have forgotten my log in details
the protocol, it states that the intervention must be carried out for
5 minutes per cycle. How strict is this policy
REPAIR patients may require cytokine samples to be taken over the weekend.
What should happen in these circumstances as there may not be staff available
to carry this out?
it is possible to collect some but not all samples, which are the most
important ones to choose?
the eCRF it lists a schedule of follow up appointments with populated
dates. How near to this date does the follow need to be?
renal graft information form asks for warm and cold ischaemic times, how
should this be calculated?
one of the patients is unable to tolerate the pre conditioning, what should
if the donor lives abroad? Can I still recruit a pair if the donor lives
abroad and will be returning home after their operation?
training the issue of what would happen if a patient has a working fistula
in both arms has been raised on a few occasions. Should we use the leg
for pre conditioning?
if a pair is randomised but the transplant is cancelled at the last minute?
on anti-TNF alpha treatment be included in REPAIR?
on amiodarone be excluded from the trial?
the interventions be carried out?
an Intention to Treat (ITT) trial, what does that mean?
Can the preconditioning
stimulus be applied immediately before or even during a dialysis session?
avoid fizzy drinks, coffee, tea, hot chocolate or anything containing
caffeine or chocolate on the morning of or during the iohexol test?
If the patient
is not weighed on the day of the Iohexol clearance can the weight recorded
around the date of the 12 month follow up be used instead?
function of the transplanted kidney be affected by iohexol (which is a
Why does the
trial use iohexol GFR as the primary endpoint, rather than a nuclear medicine
specifies CellCept mycophenolate mofetil (MMF). Is it acceptable to use
have contacted the REPAIR nurse at the hospital asking if they are allowed
to have a decaffeinated drink prior or during the Iohexol test. Is this
If a patient
is randomised but for some reason (e.g. staffing issues) the interventions
are not carried out but the transplant goes ahead should the patient be
Does the PI
have to sign off the CRF?
receiving Campath (alemtuzumab) induction be excluded from the study?
Are patients who are receiving intravenous immunoglobulin (IVIG) excluded from REPAIR?
updated 29 November 2012